A 2025 meta-analysis pooling three trials (878 participants) confirmed the pattern: significantly greater weight loss than placebo about ~14% of total body weight on average with no significant rise in overall adverse events [6] [7]
Symptoms included extreme jaundice, constant nausea, vomiting, severe constipation, stomach swelling and extreme fatigue
Preserving Muscle on Weight Loss Drugs: Key Takeaways Dont Skip Protein Ensure adequate protein intake to support lean muscle
The traffic is not bad, its extremely walkable, it feels very safe, there is a ton of greenspace, its cheap, and while it is making its way onto many new hot lists of travel, it is still so under-touristed that just about every bar and restaurant relies on locals and it is hard to get a bad meal, something that has become painfully easy to do in crowded parts of the much more visited cities