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Synergistic pathways allow lower tretinoin levels for equal efficacy while niacinamide buffers irritation and azelaic acid targets pigment, simplifying regimens and improving adherence
It also has a collagen-boosting effect to improve the skins natural firmness, filling fine lines and wrinkles and injecting softness into dry, thirsty, leathery skin
L- L- , 2000
Bibcode:2011ChEuJ..1710151H
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