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Nicotinamide N-methyltransferase (NNMT) inhibition increases energy expenditure and decreases fat storage, two important aspects of treating insulin resistance, a defining feature of type 2 diabetes
The 2026 Clinical Obesity review found GLP-1 users running 2630% lower ferritin than comparison groups, and a separate analysis of 18,746 adults with type 2 diabetes found GLP-1 users had a 54% higher likelihood of lower ferritin than users of a different diabetes drug class
Your doctor may be able to recommend a specific brand of supplements
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It has to be injectable
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