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Postmarketing surveillance data and real-world evidence from GLP-1 receptor agonists that have been available for over a decade (such as liraglutide and exenatide) have yielded mixed results
[62](n.d.)
Though there are exceptions, these remedies are generally only taken one to four times per day and/or for a short time period
As predicted, GEP12 elicits little to no GLP-1R internalization, a finding that is consistent with and confirms the observations of 49 , and is consistent with the concept of biased agonism
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