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15,16 In patients with clinical symptoms of vitamin B 12 deficiency and low levels of serum vitamin B 12 , no further confirmatory testing is generally needed before treatment is initiated
40 However, these drugs are not being developed due to concerns about affecting host glucose uptake
To mitigate these risks, professional societies recommend discontinuing once-weekly GLP-1RAs at least one week prior to surgery
Theoretical Risks and Safety Nuance Preclinical Safety Observations While no major adverse events are reported in the limited human data, researchers note theoretical concerns based on animal models
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