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It reflects a genuinely novel mechanism that explains why the clinical outcomes have been so striking, not just for diabetes and weight loss, but potentially for conditions like PCOS where metabolic dysfunction drives the disease
Patients ranged in age from 19 to 71 years of age (mean age 51) and 70% were female
Similar inverse associations between riboflavin intake and blood estradiol levels were found by the Nurses Health Study II, which is one of the longest running investigations of factors influencing womens health ( n = 116,469) by combining food-frequency questionnaires (FFQs), health surveys, and biological samples (urine, blood and cheek cell samples) 87
