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Under conditions of increased energy expenditure (cold temperatures, physical exercise), they can release energy as heat and counteract obesity
This has created a large group of non-diabetic patients who take these medications to manage their weight
7 In patients who meet these criteria, the ADA preferably recommends use of a GLP-1 RA with proven cardiovascular benefit or an SGLT-2 inhibitor with proven cardiovascular benefit provided they have adequate kidney function
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