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When older people also lose weight rapidly, their muscle loss can be very rapid, causing them to become frail and putting them at risk for falls and fragility fractures. Called sarcopenia, this condition can be countered with increased physical activity and exercise to help maintain muscle strength and agility

A Phase II Trial of Azacitidine with Ipilimumab, Nivolumab, or Ipilimumab and Nivolumab with or without Azacitidine in Relapsed or Refractory Myelodysplastic Syndrome

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For example, other drug makers might pursue this approach going forward, compared to the more rigorous FDA approval pathway