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One unit is defined as the amount of enzyme that catalyzes the conversion of 1.0 lmol of glucose-6-phosphate into 6-phosphoglucono--lactone and generates 1.0 mol of NAD+ to NADH per minute at 37C

Most providers won't treat anyone under 14 to 18 years old (policies vary), and minors always need parental consent

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This study compared 60 mg IV edaravone for 6 cycles (24 weeks) with placebo in 137 patients with ALS and successfully met the primary endpoint of adjusted mean difference of ALSFRS-R [140]