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The level of Thr172 phosphorylation depends also on the activity of protein phosphatases [98, 99]

Subjects and methods The systematic review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines (Appendix S1) [12] and were registered with the Open Science Framework ( The literature search, data transfer accuracy, and statistics were each double-checked by at least two of the authors

In people with type 2 diabetes, this balance is disrupted, leading to persistently high glucose levels

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