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Both comparisons reached statistical significance for superiority

Data Processing, Normalization, and Validation All collected data were processed and normalized to ensure consistency and comparability across regions and time frames

10.1101/gad.343129.120 7 BourgeoisB.SpreitzerE.Platero-RochartD.PaarM.ZhouQ.UsluerS.et al (2025)

Skin Pigmentation & Tanning Melanotan II stimulates MC1R receptors in melanocytes, leading to increased melanin production . Research shows this results in darker skin pigmentation , which has been investigated for treating conditions like vitiligo and photosensitivity disorders . Why it matters: Increased melanin may help protect against UV-induced DNA damage and sunburn