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Clinical trials show non-diabetic individuals lose an average of 1022% of body weight over one year, with results varying based on genetics, starting weight, and lifestyle support

Despite prior patient education and adherence to antidiabetic therapy, persistent vomiting and carbohydrate deficiencylikely related to GLP-1 RA side effectsled to decreased insulin administration and metabolic decompensation

Blood pressure changes may occur in some Ozempic users

In the STEP 1 trial extension, participants who had lost an average of around 15 percent of body weight were left with a net loss of only about 6 percent two years after stopping