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Acute JNK activation can be pro-apoptotic (e.g., in response to TNF- or oxidative stress), but it also plays essential roles in cell survival, metabolism, and tissue repair depending on the duration of activation and the cellular environment (70)
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\n\n\n\n In gastrointestinal research specifically, the nitric oxide pathway is closely involved in maintaining mucosal integrity, which aligns directly with BPC-157s observed gastroprotective properties and its origin in gastric juice protein
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