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Efficacy, safety, and tolerability of oral semaglutide versus placebo added to insulin with or without metformin in patients with type 2 Diabetes: the PIONEER 8 trial

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Important safety information: GLP-1 medications carry an FDA boxed warning about thyroid C-cell tumors seen in animal studies and are contraindicated with a personal or family history of medullary thyroid carcinoma (MTC) or MEN2

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(1998), European Journal of Endocrinology

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