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While the exact mechanisms through which semaglutide exerts its cardiovascular benefits are not fully understood, several theories have been proposed: The positive impact of semaglutide on cardiovascular outcomes has created a new paradigm in treating type 2 diabetes, where the cardiovascular benefit is now a key consideration in selecting an antidiabetic therapy

Absorption rates by injection site Three primary subcutaneous injection sites are used for GLP-1 agonists, and they do not absorb at the same rate: The abdomen has the richest subcutaneous blood supply of the three sites, which is why absorption is fastest there

Book consultations with at least two surgeons to compare expertise, communication, and comfort

PMID 16585128