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Gabrielson AT, Sartor RA, Hellstrom WJG
The studies were brief, with the first involving one of four ascending single doses over 28 days, and the second involving two or three weekly or biweekly doses over 49 days [2]
Subsequently, a stimulating effect of IGF-1 on collagen tissue in human tendon tissue is supported by in vivo studies, which have demonstrated that local administration of IGF-1 (1 mg) directly induced an elevation in collagen synthesis in human tendon tissue (Nielsen et al., 2024)
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