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The risk of MACE was reduced by 12% (HR 0.88, 95% CI 0.840.94) with GLP-1RAs and by 11% (HR 0.89, 95% CI 0.830.96) with SGLT2is compared with that in placebo groups, suggesting that GLP-1RAs and SGLT2is reduce the risk of MACE to a similar extent

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The following foods have high histamine levels: Alcohol Pickled or canned foods sauerkrauts Matured cheeses Smoked meat products salami, ham, sausage Shellfish Beans and pulses chickpeas, soy beans, peanuts Nuts walnuts, cashew nuts Chocolates and other cocoa based products Vinegar Ready-made meals Salty snacks, sweets with preservatives and artificial colorings The following foods can trigger the release of histamine: Most citric fruits kiwi, lemon, lime, pineapple, plums Cocoa and chocolate Nuts Papaya Beans and pulses Tomatoes Wheat germ Additives benzoate, sulphites, nitrites, glutamate, food dye The following foods can block diamine oxidase (DAO), an enzyme that helps break down histamine: Alcohol Black tea Energy drinks Green tea Mate tea If that seems like a lot of things to avoid, lets shift gears and focus on things that are low in histamine there are still plenty of things to eat

Vitamin B12 is water-soluble, so excess amounts are generally excreted in the urine