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Hepatocyte cultures characterise effects on glucose output (where glucagon signalling raises and incretin signalling lowers), lipogenic gene expression, mitochondrial function, and lipid oxidation pathway activation

Lean mass is not just muscle Lean body mass includes: Skeletal muscle Organs Bone Body water Connective tissue This means that not all lean mass loss reflects a loss of muscle

This ensures the treatment remains effective and allows for adjustments if needed

CAN CAN is characterized by impaired autonomic control over cardiovascular function, resulting from damage to the sympathetic and parasympathetic fibers that innervate the heart and blood vessels