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Nausea is the most common side-effect GLP-1 symptom, followed by vomiting, sour burps, heartburn and gastroparesis Side-Effect Profile of GLP-1s, from Worst to Best (% reflects estimated number of patients with GI side-effects) 50% Semaglutide (Ozempic, Rybelsus, Wegovy) 40% Tirzepatide (Saxenda, Mounjaro) 40% Liraglutide (Victoza, Saxenda) 30% Lixisenatide (Adlyxin USA, Lyxumia UK) 10% Dulaglutide (Trulicity) 10% Exenatide (Byetta, Bydureon) Wegovy, Mounjaro, and Saxenda FDA-approved for weight loss
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A total of six microbial taxa were found to have adverse interactions, whereas Hungatella and Fusicatenibacter showed favorable associations, with Butyricicoccus, Clostridium, Desulfovibrio piger, Parabacteroides merdae , and Hungatella showing positive correlations, with the depressive phenome
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