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First isolated in 1974 by Swiss researchers Schoenenberger and Monnier from the cerebral venous blood of rabbits during electrically induced slow-wave sleep, DSIP was the first endogenous peptide identified specifically in the context of sleep regulation

Supports tissue regeneration and contributes to healthier, more radiant skin

Nausea, vomiting, diarrhea, and constipation are common during dose escalation

Furthermore, it is of note that the changes of gene mRNA expression do not directly reflect the enzyme activities or protein functions, therefore, the regulatory mechanisms of L-carnitine at the transcriptional level still need further functional validation