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Side effects: GLP-1 medications are frequently associated with nausea, constipation, gastroparesis, and, in some patients, significant muscle mass loss alongside fat loss
The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions
Blood tests reveal lower glutathione levels in Alzheimers patients compared to healthy individuals
doi: 10.1007/s00125-023-05988-3 146
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