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Clinical consequences of such malnutrition can lead to impaired muscle function, decreased wound healing, altered ventilatory response, and abnormal immune function [54]

The coupling of A-GSH targeting ligands resulted in significantly higher BBB penetrations for the 3-PLG-dopa-A-GSH nanocarriers both in the presence of organoids from healthy (3-PLG-dopa-A-GSH P app : 6.52 10 6 cm/s) and PD cells (3-PLG-dopa-A-GSH P app : 6.80 10 6 cm/s) compared to the permeability values of non-targeted formulations

The 0.9% is the optimal balance

Spearmans rank correlation analyses suggested a significant, positive monotonic association between vitamin B 12 levels and TT