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The SURMOUNT-1 trial demonstrated mean body weight reduction of 20.9% at 72 weeks on tirzepatide 15mg weekly versus 3.1% placebo
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Taking account of the mechanisms of ferroptosis, GSH-depleted methods have been extensively exploited for antitumor therapy based on GSH-enhanced GPX4 inactivity and LPO accumulation
Myo-inositol oxygenase overexpression accentuates generation of reactive oxygen species and exacerbates cellular injury following high glucose ambience: A new mechanism relevant to the pathogenesis of diabetic nephropathy
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