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Inhibition of Krebs cycle in normal prostate cells leading to accumulation and secretion of citrate, which is predominantly obtained via the suppression of m-aconitase, due to an accumulation of zinc in normal prostate cells [85]
Casida J, Quistad G., (2004)
Based on the literature, ligands of the transferrin, insulin and leptin receptors, and low density lipoprotein receptor-related proteins (LRPs) are used to shuttle pharmaceutical agents across the BBB in preclinical studies [18, 28]
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