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In frail elderly patients or those with multiple comorbidities, clinicians may opt for even slower titration schedules or lower maintenance doses to balance efficacy with tolerability
Statements Author contributions EJ conducted the literature search, summarized these data, and drafted the review
Watanabe, S., Ajisaka, R., Masuoka, T., Yamanouchi, T., Saitou, T., Toyama, M., Takeyasu, N., Sakamoto, K., and Sugishita, Y
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