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Currently, different groups are developing methods to overcome these issues based on the incorporation of vascular endothelial growth factor (VEGF) and WNT7b or co-culture methods with mesodermal progenitors generating a vascular networks (Shi et al., 2020
This matrix serves a foundation supporting the migration of epithelial cells, keratinocytes, and microvascular structures [535]
Tateishi N et al
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therefore, in vivo studies in SCD mice to demonstrate in more detail a physiological significance of the TSS pathway in alleviating oxidative and ferroptosis stress are warranted
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