Around three and a half years ago, my then internet friend (and now my cofounder at my virtual clinic, Vineyard), Spencer Nadolsky, DO, tweeted something that hit me hard
In cell experiments, GLP-1 was found to have more mechanisms that may inhibit liver fat synthesis, such as FAM3A, NRF2, NaB, SHP1/AMPK, NLRP3, FGF21, IRS2, and other signaling pathways, which also provided direct evidence for the role of GLP-1R in the regulation of lipid metabolism in the liver
This unregistered medicine has not been evaluated by SAHPRA for its quality, safety or intended use
Gejl M, Gjedde A, Egefjord L, Mller A, Hansen SB, Vang K, et al