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Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning
Over the longer term, once weight stabilizes, GLP-1 medications appear to lower uric acid and reduce flare frequency, leaving patients better off
The pharmacokinetic profiles differ enough that what worked for one may need adjustment for the other
Their primary effects include: reducing hunger signals in the brain slowing gastric emptying so people feel full longer improving insulin secretion in response to food stabilizing blood sugar levels Because of these effects, GLP-1 therapies have become widely used in metabolic medicine and obesity management
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