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It is possible that compensatory mechanisms could develop that reduce efficacy with prolonged use
DSIP is a synthetic nonapeptide (nine amino acids, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu), supplied as a lyophilized powder
To establish a connection with the NO-system, l-NAME (5 mg/kg intraperitoneally) (worsening) and/or L-arginine (100 mg/kg intraperitoneally) (beneficial effect) were given alone or together
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