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It should be taken first thing in the morning, at least 30 minutes before eating, drinking, or taking any other medications

[23] Regulation [edit] Aside from deactivating radicals and reactive oxidants, glutathione participates in thiol protection and redox regulation of cellular thiol proteins under oxidative stress by protein S -glutathionylation, a redox-regulated post-translational thiol modification

It also matters for accuracy at high doses, because you can fit the entire dose within a 1 ml syringe up to 20 mg

Consuming small, frequent meals and limiting high-fat, fried, or greasy foods can help reduce these side effects, Vocca says