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In a mouse model of shoulder arthrofibrosis, multiple intraarticular injections of human relaxin-2 restored range of motion and eliminated capsular fibrosis

Tolerance to GLP-1 medications is not dose-frequency dependent

doi: 10.1007/s00296-011-1999-3

Route of administration is also mechanistically relevant: injectable BPC-157 achieves local tissue concentrations not accessible via oral dosing, which matters when the target is intra-articular or peri-articular

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