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The thigh: slower absorption with fewer side effects The front of the thigh is the second most popular injection site, and it has advantages that make it the preferred choice for a significant subset of GLP-1 users

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A systematic review of the antidepressant effects of glucagon-like peptide 1 ( GLP-1 ) functional agonists: Further link between metabolism and psychopathology Special Section on Translational and Neuroscience Studies in Affective Disorders

Significant weight loss from tirzepatide may reduce levothyroxine requirements in some patients, necessitating TSH monitoring at baseline, after substantial weight loss, and every 6-12 months once stable