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6-8 One key misunderstanding is that this is a disease of just lack of willpower, when in fact there is underlying biology that may impede people with obesity from losing weight and keeping it off
Similarly, systemic TB-500 administration in rats, dogs, and primates was well tolerated up to 60 mg/kg intravenously, with no histopathological abnormalities reported
Some examples include: GLP-1 agonists (e.g., semaglutide, liraglutide): Used for the treatment of type 2 diabetes and obesity
