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It acts as a non-selective agonist at MC1R, MC3R, MC4R, and MC5R, with particularly high potency at MC1R, the receptor governing melanogenesis in epidermal melanocytes via the cAMP-PKA-MITF pathway
Prior Authorization/Non-Formulary, Wegovy (semaglutide) - Cardiovascular Risk Reduction Only
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If digestion slows too much, gastroparesis (also known as delayed gastric emptying) and gastroenteritis (among other side effects, some life-threatening like ileus which is similar to gastroparesis but happens in the intestines,) can occur
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