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This study was approved by the Mass General Brigham institutional review board and granted waiver of informed consent because only deidentified claims data were used

Understanding N-Acetylcysteine (NAC) N-acetyl-cysteine (NAC) is an important amino acid derivative and precursor to glutathione ( 3 )

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Completed Phase II and III clinical trials have indicated that the agent has a nonoverlapping toxicity profile and synergistic effects with carboplatin, paclitaxel, and anthracycline, has no cross-drug resistance and is well tolerated, with patients mostly reporting fatigue and nausea