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Diet, supplements (e.g., niacin, NR), and exercise help, but may not suffice post-40 due to inefficiency and depletion.[18][19] Oral precursors like NMN increase NAD+ but bioavailability varies
If you are concerned at all about methionine, AgelessRx recommends a short-term B12/MIC protocol
A B12 shot is administered by injecting vitamin B12 directly into muscle tissue, typically in the upper arm, thigh, or hip
This reaction effectively diverts nicotinamide away from the NAD+ salvage pathway, reducing the cell's capacity to regenerate NAD+
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