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These projections from the area postrema to the RVLM may constitute potential pathways activated by GLP-1 to elicit sympathetic responses

Pantalone, DO, ECNU, FACE, professor of medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, director of diabetes initiatives and staff endocrinologist in the department of endocrinology at Cleveland Clinic, told Healio | Endocrine Today

Its caffeine, chlorogenic acid, and saponins act as sympathomimetics that may enhance lipolysis, but the article says none of those mechanisms trigger GLP-1 release or bind the GLP-1 receptor