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C-MET927-LZ c-MET (amino acids 1927) followed by a GGGGS linker, a GCN4 zipper sequence (RMKQL EDKVE ELLSK NYHLE NEVAR LKKLV GER), HR3C, Tsi3 tag, and His6 tag, was cloned into the pEZT-BM vector (Supplementary Table 1)
EgerodKLEngelstoftMSGrunddalKVNohrMKSecherASakataIet al
The gradual dose escalation helps balance efficacy with patient comfort, as the peptides triple-agonist action on glucagon, GIP, and GLP-1 receptors supports sustained glucose regulation
Borghetti, G., von Lewinski, D., Eaton, D
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