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In Phase 3 TRIUMPH-4, retatrutide at 12 mg produced 28.7% body weight loss at 68 weeks vs 2.1% for placebo

Theyre especially handy for people with low levels of intrinsic factor, a protein that helps your body absorb vitamin B12 more easily ( Additionally, they can help those who have difficulty consuming sufficient amounts of the foods above meet their daily vitamin B12 needs

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Nature 432 , 235240 (2004)