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Clinical Evidence A study published in the New England Journal of Medicine followed 47 MCAS patients : 89% showed improvement in symptoms, including allergic, neurologic, digestive, and inflammation-related reactions Improvements happened within hours to days Only 13% experienced weight loss , and none became underweight Consistency is crucial

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It is also relevant that in recent studies, we have shown that TMAO directly interacts with human platelets (both isolated and in whole blood), altering stimulus-dependent calcium signaling and promoting platelet hyperresponsiveness (4)

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