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Concurrently, it disrupts the function of -ketoglutarate-dependent dioxygenases, perturbs the balance of histone methylation, and synergistically drives malignant tumor progression through AMP-activated protein kinase (AMPK)/mTOR-mediated metabolic reprogramming

Abstract Currently, neuropathic pain is an underestimated socioeconomic health problem affecting millions of people worldwide, which incidence may increase in the next years due to chronification of several diseases, such as cancer and diabetes

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