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Inflammation and immune modulation Tirzepatide reduces circulating inflammatory markers including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha)
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GLP-1RAs are generally recommended for patients with T2D whose glycated haemoglobin (HbA 1c ) is above target despite diet, exercise and existing glucose-lowering medication, and GLP-1RAs with proven cardiovascular benefit are also recommended in patients with T2D at elevated cardiovascular risk, regardless of HbA 1c [5, 6]
Diabetes 69 , 10001010 (2020)
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