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The FDA approved Zepbound for chronic weight management in November 2023, and later expanded it to obstructive sleep apnea in adults with obesity

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It is important to emphasise several key points: Evidence relates to semaglutide at weight management doses (2.4 mg) , not specifically to Ozempic at diabetes treatment doses Studies have focused on osteoarthritis , not rheumatoid arthritis or other inflammatory arthropathies Long-term data on joint outcomes remain limited Individual responses vary considerably For rheumatoid arthritis and other inflammatory forms of arthritis, there is insufficient evidence to suggest that Ozempic or weight loss alone would adequately control disease activity

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