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Non-pharmacological interventions form the foundation of treatment: Exercise therapy : Aerobic exercise, strength training, and flexibility exercises have the strongest evidence base

When you look at the therapeutic landscape, what stands out is that muvalaplin (from Eli Lilly and Company) is currently the most advanced, and the first oral small molecule to demonstrate robust Lp(a) lowering in humans, specifically developed for this target, while most of the field is focused on injectable siRNA and antisense approaches

Semaglutide is usually started at a lower dose to help reduce side effects, and the effects may become more noticeable as the medication builds over time or as the dose increases