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[40] Endogenous vitamin B 12 becomes inactive when exposed to hydrogen cyanide and nitric oxide in cigarette smoke
Ness-Abramof R, Nabriski DA, Braverman LE, et al
Risk rises when factors accumulate, for example dose escalation, timing near large meals, existing reflux, or diabetic neuropathy, and a small subset of users, about 1 in 50 (2%), report persistent hiccups that need clinical attention
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