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The FDA Adverse Event Reporting System (FAERS) contains reports of musculoskeletal complaints associated with GLP-1 use, but such reports do not prove causation and may reflect coincidental associations or other contributing factors

The product is not authorised by the MHRA as a human or veterinary medicine, and purchasers are responsible for compliance with their institutional research-governance framework

Some patients report persistent gastrointestinal symptoms that may affect quality of life and nutritional status

[8] detoxification of acyl groups by forming acylcarnitine, which is then excreted to prevent the accumulation of potentially toxic fatty acyl intermediates