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Different antibody isotypes have different flexibilities that might affect how the two Fab arms of an antibody interact with virion surface proteins, both in terms of intrinsic affinity and avidity through bivalent binding

To mitigate this risk, researchers should investigate combination strategies, adaptive dosing regimens, and mechanisms to prevent bacterial efflux of silver ions

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Pregnancy or breastfeeding, certain cancers, uncontrolled endocrine disorders, and medication interactions can be contraindications depending on the peptide