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[13] Activation [edit] Carnitine shuttle activation occurs due to a need for fatty acid oxidation which is required for energy production

This pathway safely degrades homocysteinea potentially toxic byproduct of metabolisminto cysteine through two sequential enzymatic steps involving cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE)

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What the Clinical Trial Data Shows for Retatrutide Phase 2 clinical trial results, published in the New England Journal of Medicine, demonstrated that retatrutide produced mean body weight reductions of 17.5% at the 4mg dose and 24.2% at the 12mg dose over 48 weeks in adults with obesity [8]