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Individuals with reduced bile acid reabsorption efficiency may develop worse diarrhea or cramping when GLP-1 agonists further slow transit and alter intestinal pH
Tesamorelin is a growth hormonereleasing hormone (GHRH) analog, while Ipamorelin is a ghrelin receptor agonist
GLP-1R agonists show great potential in AD, but key challenges, such as blood brain barrier (BBB) penetration, clinical trial inconsistency, long-term safety and precision therapy, need to be addressed
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