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This reversal was seen also on the background of the disturbed prostaglandins- and NO-systems, prostaglandins synthesis inhibition as well as NO-overstimulation (NOS-substrate L-arginine) or NO-blockade (N(G)-nitro-L-arginine methyl ester (L-NAME)) (Stupnisek et al., 2012

Some athletes swear by it for quicker injury recovery, bio-hackers are experimenting with it to optimize health, and those dealing with chronic pain are hopeful it could offer some relief

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